1 day ago · In contrast, active immunotherapy stimulates the patient’s own immune system to attack cancer cells, for example, through vaccination or chimeric antigen receptor T cell …

1 day ago · A central obstacle is immune evasion: tumor cells suppress immune responses by expressing checkpoint proteins such as PD-L1 while failing to present sufficient antigenic …

1 day ago · Hijacking the energy-producing organelles from immune cells seems to help tumours in mice to infiltrate lymph nodes.

2 days ago · According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody …

May 10, 2024 · Authors note that tumors likely employ a variety of strategies to evade immune detection. But the discovery could lead to a new approach for targeted cancer therapies.

Nov 27, 2025 · Recent studies suggest that tumor cells may hijack CD300a-associated pathways to establish an immunosuppressive microenvironment that facilitates immune evasion, tumor …

Mar 13, 2025 · However, tumor cells have developed sophisticated ways to evade detection, including hijacking the immune system’s brake mechanism, known as immune checkpoints.

Aug 5, 2025 · A comprehensive analysis published in Reserch illuminates how cancer cells hijack immune checkpoints on natural killer (NK) cells to disable the body’s frontline defense system.

Dec 16, 2025 · Even if a T-cell recognizes a cancer cell, the tumor employs a second strategy to shut down the immune attack through molecular signaling. This involves exploiting natural …

3 days ago · The Development of Immune Checkpoint Inhibitors Years of NCI-funded basic research investigated the hypothesis that the immune system could be harnessed to stop …