A paper in PNAS this week reporting that a signature of microRNA (miRNA) gene expression correlates with diagnosis and prognosis of B-cell chronic lymphocytic leukemias (CLLs) has drawn skepticism ...

Croce, along with colleagues at Ohio State, Thomas Jefferson University and three cancer centers in Italy, used a microarray containing all known miRNA to examine miRNA activity in 76 breast tumors.

As a result, Agilent has developed a microarray tool to characterize miRNA-expression patterns and recently introduced a commercially available human miRNA microarray.

Microarrays allow many more samples to be profiled in tandem, however this method is usually more expensive. A more novel approach to miRNA profiling is next-generation sequencing.

This finding sets the stage for additional studies to identify microRNA biomarkers in other tumors using microarrays and quantitative reverse transcriptase PCR (RT-PCR).

This report also examines recent studies, microRNA detection, and profiling, clinically oriented microRNA profiling in several human cancers.

Researchers can use Agilent’s pre-designed human, mouse or rat miRNA probes, or access miRNA sequences for all 87 species in Sanger 12.0 in the designs of their miRNA microarrays.

4062 Background: In previous miRNA microarray studies in gastric cancer, adjacent non-tumor tissue was used as the control as opposed to tissue from healthy volunteers. Also, most of previous studies ...

Using a custom microarray, we studied the global microRNA expression in 12 nontumor pancreas and 44 pancreatic primary tumors, including 12 insulinomas, 28 nonfunctioning endocrine tumors, and four ...

Frost & Sullivan has released a new report showing that the U.S. MicroRNA Market earned revenues of over $20.3 million in 2008. The firm estimates this to reach $98.6 million in 2015.