When only one allele of a gene is actively transcribed, gene expression is termed monoallelic. What does monoallelic gene expression have to do with cats, twins, and genetic diseases? Therefore, ...

Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin. The exact cause of T1D remains ...

1-Aminocyclopropane-1-carboxylate synthase (ACS) catalyzes the rate-limiting step in the ethylene biosynthetic pathway in plants. The Arabidopsis genome encodes nine ACS polypeptides that form eight ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

The expression of ACE2 is upregulated in smokers, but not affected by sex and age. Amino acids that form polar contacts between ACE2 and RBD are essential for binding. Variants may change binding ...