When only one allele of a gene is actively transcribed, gene expression is termed monoallelic. What does monoallelic gene expression have to do with cats, twins, and genetic diseases? Therefore, ...
Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin. The exact cause of T1D remains ...
1-Aminocyclopropane-1-carboxylate synthase (ACS) catalyzes the rate-limiting step in the ethylene biosynthetic pathway in plants. The Arabidopsis genome encodes nine ACS polypeptides that form eight ...
Our research in this area includes uncovering fundamental mechanisms that regulate how genes are turned on and off in normal cells and how the misregulation of these mechanisms can lead to cancer, as ...
Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, ...
The expression of ACE2 is upregulated in smokers, but not affected by sex and age. Amino acids that form polar contacts between ACE2 and RBD are essential for binding. Variants may change binding ...
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