Wnt proteins function as morphogens that can form long-range concentration gradients to pattern developing tissues. Here, we show that the retromer, a multiprotein complex involved in intracellular ...

The most widely used technique for finding the largest or smallest values of a math function turns out to be a fundamentally difficult computational problem. Many aspects of modern applied research ...

In particular, an oxygen gradient exists between healthy and damaged heart tissue, but it has been difficult to investigate how this gradient affects the function of the heart.