Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

Adjuvant Nivolumab in High-Risk Muscle-Invasive Urothelial Carcinoma: Expanded Efficacy From CheckMate 274 Sixteen towns in Sihui and Zhongshan cities, China, were selected; eight were randomly ...

Background: Although most patients with low back pain (LBP) recover within a few weeks a significant proportion has recurrent episodes or will develop chronic low back pain. Several mainly ...

In an open-label, two-period, two-sequence, cross-sectional, cluster-randomized, crossover trial, we assigned hospitals in Ontario, Canada, to use either lactated Ringer’s solution or normal saline ...

Medical podcast integration into hematology/oncology fellowship curricula remains largely unstudied. We conducted a multicenter cluster randomized trial to evaluate the educational impact of a podcast ...

Among randomized hospitalized patients in this trial, routine use of lactated Ringer’s (LR) solution did not reduce the risk of death or re-hospitalization compared to normal saline (NS). 2. No ...

While insecticide-based interventions help reduce malaria's disease burden, rising resistance and evolving behavior by the malaria-spreading anopheles mosquito threaten that progress. In a ...

Ivermectin is an antiparasitic drug that kills mosquitoes feeding on treated persons. In this trial in Kenya, ivermectin given once per month for 3 months led to a 26% lower incidence of malaria than ...

Men with risk factors for osteoporosis are identified for a nurse-led program that greatly enhances the rate of screening and treatment adherence.