Chloroplast gene expression is governed by a sophisticated network of nuclear‐ and plastid‐encoded factors that integrate transcription, RNA processing and translation. Central to this process is the ...

We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA ...

Researchers at the University of Barcelona reveal that RTP801, a protein elevated in Alzheimer’s patients, disrupts RNA processing and protein synthesis, exacerbating cognitive decline. This discovery ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

SAN CARLOS, Calif. & EMERYVILLE, Calif. Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, ...