Yes, you can create workflows for SharePoint lists in SharePoint Designer, but they aren't the most robust workflows you may need for your organization.

Microsoft on Monday gave notice that it will be ending support this year for the 'workflows' component of SharePoint 2010 Online, as well as deprecating that component for SharePoint 2013 Online.

SharePoint workflows are based on Windows Workflow Foundation (WF) which is a base set of technologies that programmers can access using Visual Studio or SharePoint Designer.