The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a ...

Bispecific antibodies can be manufactured in bulk, stored, and delivered like traditional antibody drugs. This means they ...

St. Jude scientists have uncovered the previously unknown lipid-regulated mechanism that initiates LC3-associated ...

Cigarette smoke impairs mesenchymal stem cell function, limiting proliferation, migration, differentiation, and ...

The immune system is comprised of two separate active arms of immunity to provide robust protection against disease. The two separate systems of immunity include the innate and adaptive immune ...

During gestation, the placenta takes on the roles of many of the fetus’ developing organs and serves as a barrier between parent and child. Critical to this is the outermost layer of the organ, the ...

In the brain, it is not only important that nerve cells send signals, but also how quickly they can do so. In order for ...

Yale School of Medicine-led research reports that nerve-associated macrophages help maintain healthy fat over a lifespan and curb age-related inflammation.