Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

Localized scleroderma is a rare connective tissue disorder characterized by hardening and thickening of the skin due to increased collagen density. A quarter of patients affected also experience ...

Padua, Italy - Although juvenile localized scleroderma is typically thought of as a skin disease, Dr Francesco Zulian reports in the September 2005 issue of Arthritis & Rheumatism that 22.4% of ...

Given the potential significant morbidity of linear scleroderma, it is important to identify treatment approaches that can improve outcomes. This study provides another dataset that supports the use ...

Fibrocell Science has submitted an Investigational New Drug Application (IND) with the FDA for a gene therapy candidate to treat moderate to severe localized scleroderma. Fibrocell Science has ...

Durham, NC - A study released today in STEM CELLS Translational Medicine suggests a new way to correct facial atrophy of localized scleroderma (LoS) in patients. It shows how applying grafts made up ...

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Clinical enrollment for an open-label, single-arm Phase 1/2 trial of FCX-013 was initiated in August 2018. Fibrocell Science announced that the Food and Drug Administration (FDA) has granted Fast ...

Long-term methotrexate therapy was a beneficial, well-tolerated treatment for juvenile localized scleroderma, according to study results. Researchers in Italy evaluated 65 patients with juvenile ...

Scleroderma diagnosis is rather difficult as the symptoms of the disease overlap with those of other conditions. Therefore, it becomes necessary to rule out other auto immune diseases before focusing ...

Scleroderma is a rare and often fatal disease, causing the thickening of tissue, that currently lacks a cure and any effective treatments. A group of researchers is looking to change that. The group ...