We present a simple sample-size formula for weighted log-rank statistics applied to clustered survival data with variable cluster sizes and arbitrary treatment assignments within clusters. This ...

Health-related quality of life (HRQoL) instruments are increasingly used as outcome variables in clinical trials, leading to a requirement for sample size calculations based on these variables. This ...

Pharmacokinetic modeling demonstrated that the formula was reasonably accurate regardless of whether a one- or two-compartment model most accurately described carboplatin pharmacokinetics, assuming ...