Two-stage randomized trials are growing in importance in developing adaptive treatment strategies, i.e. treatment policies or dynamic treatment regimes. Usually, the first stage involves randomization ...

Mathematics of Operations Research, Vol. 42, No. 3 (August 2017), pp. 692-722 (31 pages) In many computing and networking applications, arriving tasks have to be routed to one of many servers, with ...

In many situations, proper randomization is crucial for the validity of any conclusions to be drawn from an experiment. Randomization is used both to neutralize the effect of any unknown systematic ...

In a randomized complete block design (RCBD), each level of a "treatment" appears once in each block, and each block contains all the treatments. The order of treatments is randomized separately for ...

An evaluation of the societal costs and benefits of adjuvant trastuzumab in the treatment of early HER2neu-positive breast cancer in Singapore. Background: The era of cytostatic cancer agents requires ...

Predictive Value of Bone Resorption and Formation Markers in Cancer Patients With Bone Metastases Receiving the Bisphosphonate Zoledronic Acid To compare the variability and sample size requirements ...