TypeScript 4.7 and 4.8 introduce ES Module (ESM) support for Node.js, improved type inference and control flow analysis, and significant performance improvements.

Deno is a rethink of a server-side JavaScript runtime from original Node.js creator Ryan Dahl, to address regrets and challenges with Node.js.

Node.js, which can work with TypeScript, has been working to support ECMAScript modules (ESM), which enable packaging of JavaScript code for reuse.

However, unlike Node.js, Deno offers first-class support for Microsoft's increasingly popular Typescript, a superset of JavaScript designed for large projects.