Genomic testing based on chromosome microarray (CMA) and Next Generation Sequencing (NGS) revolutionized clinical genetics. That said, microarray, targeted panel, exome and generic whole genome ...

A role for BRCA1 in the direct and indirect regulation of transcription is well established. However, a comprehensive view of the degree to which BRCA1 impacts transcriptional regulation on a ...

The arrival of next-generation sequencing (NGS) technology has revolutionized the field of genomics and expanded the scope of scientific inquiry to sequence datasets from multiple genomes and ...

Analysis of the human transcriptome is often limited to annotated sequences. In the May 3 Science, Philipp Kapranov and colleagues at Affymetrix Inc., California provide evidence for many undiscovered ...

Plowing through Transcriptional Variations by Harnessing the Powerful Next-Gen Technique Advances in genomics over the past several years have had a profound impact on our grasp of molecular biology ...