Some quick example code for parameter estimation with an SIR model, as well as for examining identifiability and uncertainty using the Fisher information matrix and profile likelihoods---see lab ...
GitHub

SIR_MultiStart_Save.m

% This code fits a SIR model for LA county data on COVID-19 - https://github.com/datadesk/california-coronavirus-data and http://publichealth.lacounty.gov/media ...