We propose the warped linear mixed model (WarpedLMM), a principled generalization of the standard LMM that allows to fit phenotype transformations while performing genetic analyses.

Sanjoy K. Sinha, Robust Analysis of Generalized Linear Mixed Models, Journal of the American Statistical Association, Vol. 99, No. 466 (Apr., 2004), pp. 451-460 ...

However, the utility of linear (mixed) models in the context of meta-analysis of GWAS of binary phenotypes has not been previously explored.

Xihong Lin, Jonathan Raz, , Linear Mixed Models with Heterogeneous within-Cluster Variances, Biometrics, Vol. 53, No. 3 (Sep., 1997), pp. 910-923 ...