How to compare columns in Microsoft Excel As stated, we can use the Excel VLOOKUP function to find and match different data or find differences in two columns.

If you need to reconcile batches of records in Microsoft Excel, this simple VLOOKUP() solution offers a quick and easy way to find records in one batch that are missing from another.

A row-by-row formatting rule is as easy to apply as a column-by-column in Microsoft Excel, but you might not get the results you thought you would.