A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types.

The latest imaging method from the Broad Institute uncovers structural disruptions in the nucleus associated with progeria at super-resolution.

Zhang's lab is now using ChromoGen to study how variations between neurons' genome structures and those of other brain cells might speak to those cells' specific functions.

That knowledge will help them develop other small and new genome editing tools for gene therapy. At the University of Tokyo, Prof. Osamu Nureki’s group works on identifying the structure and function ...

A new study led by researchers at the University of Cambridge, in collaboration with international institutions, has uncovered a key mechanism in how DNA behaves as it passes through nanoscale pores—a ...

First atom-level structure of packaged viral genome reveals new properties, dynamics Date: March 10, 2024 Source: University of Illinois at Urbana-Champaign, News Bureau Summary: A computational ...

MIT chemists have developed an AI-driven method to predict 3D genome structures in minutes, significantly accelerating research on gene expression and cellular functions.

We mapped the human genome decades ago, but most of it is still a black box. Now, UNSW scientists have developed a tool to peer inside and what they find could reshape how we think about disease.

These discoveries could have important medical implications, including diagnostic tests for causes of infertility linked to genome folding.