At day 5 post due pupariation time, the fat body of EcR↓ and USP↓ larvae presents 30% fewer cells and larger than normal lipid vesicles (Supplementary Figure S3A). Larvae become progressively inactive ...

The ecdysone pathway was among the first experimental systems employed to study the impact of steroid hormones on the genome. In Drosophila and other insects, ecdysone coordinates developmental ...