Chromosomes are arguably one of the most important structures inside cells. Several meters of DNA are compacted into micrometer-sized assemblies in every human cell. Recent advances in our ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Indeed, different kinds of chromosome segment inversions have been ...

Holocentric chromosomes have evolved independently from X-shaped monocentric chromosomes multiple times in both animals and plants, but the mechanism behind the centromere-type transition is unknown.

During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...

In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture ...

The development of many psychiatric disorders, including depression, schizophrenia and bipolar disorder, is known to be in ...

Some chromosomes, such as B chromosomes, can increase their inheritance rate to their own advantage. These extra chromosomes are found in many plants, animals, and fungi and rely upon various ...