The primary renal response to respiratory alkalosis is to increase the excretion of bicarbonate (HCO3-) in the urine.

GPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neurological deficits and blood-brain barrier disruption. These ...

Internal acid–base homeostasis is fundamental for maintaining life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be ...