A phase 1 dose-escalation study of intravenously (IV) administered TAK-676, a novel STING agonist, alone and in combination with pembrolizumab in patients (pts) with advanced or metastatic solid ...

Logistic regression analysis of high-dimensional data, such as natural language text, poses computational and statistical challenges. Maximum likelihood estimation often fails in these applications.

Bayesian analyses of multivariate binary or categorical outcomes typically rely on probit or mixed effects logistic regression models that do not have a marginal logistic structure for the individual ...

Please provide your email address to receive an email when new articles are posted on . Until the last decade, efforts to develop a therapy that successfully targeted the KRAS mutation had been futile ...

Please provide your email address to receive an email when new articles are posted on . “Epilepsy is one of the leading causes of lost life-years worldwide,” Ashwani Jha, PhD, of the National ...

Premature Ovarian Failure and Fertility in Long-Term Survivors of Hodgkin's Lymphoma: A European Organisation for Research and Treatment of Cancer Lymphoma Group and Groupe d'Étude des Lymphomes de ...

HDP-101, a novel antibody-drug conjugate, targets BCMA with a synthetic amanitin payload that causes tumor cell death. "I don't think I need to convince anyone here that we need to discover new ...

(Nanowerk News) Biocompatibility is a crucial goal in medical device development. For years, scientists have worked to create implant coatings and components that integrate well with the body's immune ...