Currently, PET scanner validation phantoms, methods, and acceptance criteria for clinical trials are not standardized. This situation generates substantial inefficiencies with many scanners being ...

Whole-body CD8+ T-cell PET imaging can detect spatial and temporal localization of CD8+ T cells. To obtain insight into early CD8+ T-cell response to immunotherapy in patients with melanoma, a highly ...

dosimetry radioiodine theragnostics advanced thyroid cancer Differentiated thyroid cancer (DTC) has been treated with radioactive iodine (RAI) for over 80 y (1). More than 580,000 new DTC cases were ...

Radiopharmaceutical therapy (RPT) is entering a new era of personalization, driven by advances in molecular imaging, radiopharmaceutical development, and a growing body of clinical evidence linking ...

Trustworthiness is a core tenet of medicine. The patient–physician relationship is evolving from a dyad to a broader ecosystem of health care. With the emergence of artificial intelligence (AI) in ...

1. PREAMBLE The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific and professional organization founded in 1954 to promote the science, technology, and practical ...

The nuclear medicine field has seen a rapid expansion of academic and commercial interest in developing artificial intelligence (AI) algorithms. Users and developers can avoid some of the pitfalls of ...

We propose strongly unrealistic data augmentation to improve the robustness of convolutional neural networks (CNNs) for automatic classification of dopamine transporter SPECT against the variability ...

The field of radioligand therapy has advanced greatly in recent years, driven largely by β-emitting therapies targeting somatostatin receptor–expressing tumors and the prostate-specific membrane ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

EXECUTIVE SUMMARY The value of nuclear medicine imaging for diagnosing infections, was first recognized nearly 50 y ago (1). The 3-phase bone scan was for many years the radionuclide test of choice ...

Cell Culture and Treatments The human gastric cancer cell line NCIN87 was purchased from the American Type Culture Collection. NCIN87 were cultured in RPMI 1640 growth medium supplemented with 10% ...