NFL Week 5 odds, picks, predictions, TV channel, streaming information for Thursday Night Football game between San Francisco ...

The 49ers put 12 players on their estimated report, listing seven of them as non-participants. Brock Purdy was estimated as ...

The 49ers finished 6-11 last year after stars like running back Christian McCaffrey and wide receiver Brandon Aiyuk ended the ...

The Niners laundry list of injuries finally caught up with them this past weekend as Trevor Lawrence and the Jaguars handed Kyle Shanahan’s squad their first loss. Jacksonville jumped out to a 17-6 ...

Head Coach Kyle Shanahan said that 49ers safety Malik Mustapha could be back practicing with the 49ers after Week 6.

After winning their first three games of the season, the San Francisco 49ers hosted the Jacksonville Jaguars on Sunday at Levi's Stadium and were handed their first loss of the year, falling 26-21 in ...

The San Francisco 49ers essentially imploded in their 26-21 loss to the Jacksonville Jaguars. Several plays negatively factored their implosion. However, three ...

Here are the players who won't suit up for the Jacksonville Jaguars in the team's Week 4 contest against the San Francisco ...

The San Francisco 49ers will look to start their season 4-0 for the second time under head coach Kyle Shanahan.

The San Francisco 49ers (3-0) enter a matchup with the Jacksonville Jaguars (2-1) on Sunday, September 28, 2025 at Levi's ...